Is that just North of Jacksonville?

I am going to go out on a limb and say Vegas, looking away from the strip

I think that's Reno.

I couldn't find a cityscape to match the window view, but here's what I did find.
Pic 1 found in a deviantart gallery along with the same image in your post... Same woman, same glass of wine behind her and a comment from the poster that said "Strat hotel Vegas"
Pic 2 from a travel website showing the rooms at the Stratosphere Same pillow, same lamp, same headboard... etc.

My conclusion, Owner of devianart page is probably the original photog and was telling the truth about the location and even though i couldn't find a matching view I assume that this is indeed Vegas but the photographer didn't spring for the presumably more expensive room overlooking the famous landmarks, and this is the view out behind the strip. Happy to have someone prove a better sleuth than me though. Let me know what you think of my method.

Search darylp on deviantart he has a really nice gallery of this woman. One thing I notice is that in the photo by the window she does not appear to be wearing earrings but on the bed photo she has neon green ones. She may have just taken them off or these could be from different photo sets. He seems to like taking hotel room photos. I just couldn't match up that view on Google Earth from the Stratosphere.

It's Vegas, baby
 

The building that's partially obscured by the see-thru curtain is the L'Ocitaine apartments building.

Go to google maps, put yourself on streetview at the intersection of Charleston Blvd and S Las Vegas Blvd. Looking north you see the apartment building, looking south you see the Stratosphere hotel (from where the pic was taken - thanks to the clues from inside the room).